Open AccessUptake and cellular distribution of copper, cobalt and cadmium in strains of Saccharomyces cerevisiae cultured on elevated concentrations of these metals
Author(s) -
White C.,
Gadd G.M.
Publication year - 1986
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1986.tb01738.x
Subject(s) - cadmium , cobalt , saccharomyces cerevisiae , copper , chemistry , environmental chemistry , distribution (mathematics) , biochemistry , nuclear chemistry , microbiology and biotechnology , yeast , inorganic chemistry , biology , organic chemistry , mathematical analysis , mathematics
Training by repeated culture on elevated concentrations of Co, Cu and Cd resulted in increased resistance to these metals in 3 strains of Saccharomyces cerevisiae . All the trained strains showed reduced uptake of these metals and altered intracellular distribution. Co‐trained strains showed increased Co‐accumulation in the vacuole, which was also the main compartment for Co in unstrained cells. Cd‐ and Cu‐trained cells had increased amounts of these metals in the soluble fractions of the cell, but not specifically in the vacuole. These mechanisms appeared to be distinct and to vary in their stability following detraining on metal‐free medium.