Open AccessAdherence of Fusobacterium necrophorum to bovine hepatic cells
Author(s) -
Kanoe Masamitsu,
Iwaki Kanso
Publication year - 1986
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1986.tb01536.x
Subject(s) - fusobacterium necrophorum , hemagglutinin (influenza) , microbiology and biotechnology , immunofluorescence , bacteroidaceae , strain (injury) , biology , homologous chromosome , hemagglutination , antibody , virology , chemistry , bacteria , immunology , biochemistry , gene , genetics , anatomy
The adherence of Fusobacterium necrophorum to the surface of bovine hepatic cells was investigated. Hemagglutinating strain VPI2891 adhered well to the cell membranes, whereas non‐hemagglutinating strain S‐45 adhered less well. The adherence of the former strain was strongly inhibited by the homologous anti‐hemagglutinin serum. Immunofluorescence study revealed that the purified hemagglutinin bound to the membranes of the hepatic cells. These findings suggest that the adherence of F. necrophorum to the bovine hepatic cells is mediated by the bacterial hemagglutinin and has pathogenic importance in bovine necrobacillosis.