Open AccessEvaluation of the contribution of the tyrosine pathway to the catabolism of phenylalanine in Brevibacterium linens 47
Author(s) -
Lee ChangWon,
Desmazeaud Michel J.
Publication year - 1986
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1986.tb01219.x
Subject(s) - catabolism , tyrosine , brevibacterium , phenylalanine , biochemistry , chemistry , amino acid , aromatic amino acids , biology , metabolism , bacteria , microorganism , genetics
The quantitative importance of the 3,4‐dihydroxyphenylacetate meta ‐cleavage pathway (the principal pathway of tyrosine catabolism) in the catabolism of l ‐phenylalanine in Brevibacterium linens 47 was evaluated using tyrosine‐negative mutants. Less than 5% of phenylalanine was catabolised through the tyrosine pathway. The results presented show that in B. linens the two structurally analogous amino acids are catabolised principally by separate pathways. Also, the initial pathway of phenylalanine catabolism in this bacterium has been established.