Open AccessAltered fatty acid composition in regulatory mutants of Streptomyces cinnamonensis
Author(s) -
Pospíšil S.,
Řezanka T.,
Víden I.,
Krumphanzl V.,
Vaněk Z.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb01634.x
Subject(s) - norleucine , monensin , biochemistry , streptomyces , mutant , amino acid , actinomycetales , chemistry , composition (language) , streptomycetaceae , biosynthesis , fatty acid , biology , leucine , bacteria , gene , genetics , linguistics , philosophy
Fatty acids were analyzed in the producer of monensins A and B, Streptomyces cinnamonensis C‐100‐5, and its regulatory mutants resistant to 2‐amino‐3‐chlorobutyrate, 2‐aminobutyrate and norleucine. All resistant strains were found to have a strongly increased content of even iso‐branched fatty acids. This change was also reflected in a relative increase of monensin A production, which is affected by branched amino acids.