Open AccessCharacterization of enterotoxin and soluble hemagglutinin from Vibrio mimicus : identity with V. cholerae O1 toxin and hemagglutinin
Author(s) -
Dotevall Hans,
JonsonStrömberg Gunhild,
Sanyal Suhas,
Holmgren Jan
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb01630.x
Subject(s) - vibrio cholerae , hemagglutinin (influenza) , microbiology and biotechnology , cholera toxin , enterotoxin , toxin , biology , vibrionaceae , bacteria , escherichia coli , virology , biochemistry , virus , genetics , gene
Eight strains of Vibrio mimicus isolated from patients with diarrhoea in Bangladesh were all found to produce an extracellular toxin identical to cholera toxin produced by Vibrio cholerae O1 bacteria, with regard to subunit structure and immunological properties. Like cholera toxin, but in contrast to heat‐labile enterotoxin from Escherichia coli most of the toxin from V. mimicus was found extracellularly and was proteolytically ‘nicked’ in its A subunit. This may relate to the finding that V. mimicus also produced an extracellular hemagglutinin which was immunologically indistinguishable from the soluble hemagglutinin/nicking protease of V. cholerae O1.