Open AccessLocalization of Shiga toxin gene in the region of Shigella dysenteriae 1 chromosome specifying virulence functions
Author(s) -
Timmis K.N.,
Clayton C.L.,
Sekizaki T.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb01100.x
Subject(s) - shigella dysenteriae , virulence , shiga toxin , shigella , escherichia coli , microbiology and biotechnology , biology , plasmid , locus (genetics) , gene , genetics , chromosome , toxin , shigella sonnei
R′ plasmids have been generated that contain a determinant of Shigella dysenteriae 1 which directs the synthesis of Shiga toxin in Escherichia coli K‐12. This gene is closely linked to the argE locus and thus is located in a region of the Shigella chromosome known to contain determinants of virulence factors.