Open AccessInduction of acetoacetate decarboxylase in Clostridium acetobutylicum
Author(s) -
Ballongue J.,
Amine J.,
Masion E.,
Petitdemange H.,
Gay R.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00875.x
Subject(s) - clostridium acetobutylicum , biosynthesis , biochemistry , inducer , fermentation , clostridium , chemistry , enzyme inducer , enzyme , biology , bacteria , butanol , genetics , ethanol , gene
Factors that may initiate the biosynthesis of acetoacetate decarboxylase were investigated in resting cells of Clostridium acetobutylicum . Linear acids from C 1 to C 4 were inducers, whereas branched acids and linear acids from C 5 to C 7 were not inducers of acetoacetate decarboxylase biosynthesis. Induction of acetoacetate decarboxylase was maximal at pH 4.8 in the presence of acid concentrations comparable with those found during fermentation. In growth conditions repression of acetoacetate decarboxylase biosynthesis was found. This fact explains that acetone production by Clostridium acetobutylicum occurs when growth slows down.