Open AccessDemonstration of cholera‐like enterotoxin production by Campylobacter jejuni
Author(s) -
Goossens Herman,
Butzler JeanPaul,
Takeda Yoshifumi
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00838.x
Subject(s) - enterotoxin , cholera toxin , toxin , microbiology and biotechnology , campylobacter jejuni , heat labile enterotoxin , chinese hamster ovary cell , cholera , biology , antiserum , escherichia coli , campylobacter , chemistry , bacteria , antibody , biochemistry , immunology , receptor , genetics , gene
By means of a newly developed medium, cholera‐like enterotoxin production by Campylobacter jejuni could be shown in 25 C. jejuni strains isolated from diarrheic cases. This new medium was found to yield a higher amount of enterotoxin than the two previously reported media for this purpose. Neutralization of the activity of the toxin to cause morphological changes of Chinese hamster ovary (CHO) cells by antisera against cholera toxin and heat‐labile enterotoxins of Escherichia coli (LT h and LT p ) was also demonstrated, indicating a close immunological relation of these toxins.