Open AccessLiver cell and macrophage surface lectins as determinants of recognition in blood clearance and cellular attachment of bacteria
Author(s) -
Perry A.,
Keisari Y.,
Ofek I.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00694.x
Subject(s) - phagocytosis , opsonin , macrophage , lectin , bacteria , receptor , cell , cell surface receptor , cell membrane , microbiology and biotechnology , antibody opsonization , biology , chemistry , immunology , biochemistry , in vitro , genetics
Neoglycoproteins specific for liver and phagocytic cell membrane lectins inhibited the blood clearance and the attachment to mouse macrophages of group B streptococci bearing surface sugar residues specific for the lectins. It is concluded that lectins present on the surfaces of liver, and other phagocytic cells are involved in the elimination of invading bacteria by receptor‐mediated phagocytosis, which does not require the participation of opsonins.