Open AccessSusceptibility of peritoneal macrophages to rat cytomegalovirus infection
Author(s) -
Bruggeman Cathrien A.,
Grauls Gert,
Boven Cees P.A.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00679.x
Subject(s) - cytomegalovirus , virus , virology , peritoneal fluid , macrophage , betaherpesvirinae , peritoneal cavity , inoculation , herpesviridae , biology , immunology , microbiology and biotechnology , medicine , pathology , viral disease , in vitro , anatomy , biochemistry
Peritoneal macrophages from Lewis (Lew) and Brown Norway (BN) rats did not support rat cytomegalovirus (RCMV) replication. Intraperitoneal (i.p.) inoculation of virus into the rats resulted in a rapid clearance of virus from the peritoneal lavage fluid and an uptake of virus in the macrophages. The virus did not persist in the peritoneal macrophages of the rats.