
Thiol‐stimulated secretion of riboflavin and porphyrins by Escherichia coli
Author(s) -
Javor George T.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00675.x
Subject(s) - dithiothreitol , secretion , escherichia coli , porphyrin , riboflavin , cysteine , chemistry , biochemistry , thiol , anaerobic exercise , enterobacteriaceae , biology , enzyme , physiology , gene
Under aerobic conditions, thioglycerol, dithiothreitol and cysteine stimulated stationaryphase Escherichia coli to secrete riboflavin. Thioglycerol also enhanced the secretion of porphyrins and unidentified yellow pigments. Under anaerobic conditions, thiols failed to stimulate riboflavin secretion, but 5 out of 8 thiols tested caused increased porphyrin excretion. Secretion of these substances is a manifestation of the pleiotropic response of E. coli to reductive stress.