Open AccessCa(II)‐calmodulin regulation of morphological commitment in Ceratocystis ulmi
Author(s) -
Muthukumar Ganapathy,
Nickerson Kenneth W.
Publication year - 1985
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1985.tb00667.x
Subject(s) - trifluoperazine , ceratocystis , calmodulin , mycelium , dibucaine , germination , botany , biology , basidiomycota , chlorpromazine , calcium , chemistry , biochemistry , pharmacology , enzyme , fungus , organic chemistry
The commitment phenomenon exhibited by Ceratocystis ulmi is a manifestation of the requirement for a Ca(II)‐calmodulin interaction for mycelial growth. Under otherwise identical conditions, addition of CaCl 2 (10 mM) to committed yeasts caused them to germinate, while addition of the calmodulin antagonists chlorpromazine (80 μM), dibucaine (750 μM), or trifluoperazine (60 μM) to committed mycelia caused them to bud.