Open AccessNeurotoxic and haemolytic activity of a protein isolated from Bacillus thuringiensis var. israelensis crystals
Author(s) -
Chilcott C.N.,
Kalmakoff J.,
Pillai J.S.
Publication year - 1984
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1984.tb01468.x
Subject(s) - bacillus thuringiensis , microbiology and biotechnology , chemistry , biochemistry , biology , bacteria , genetics
Two proteins (protein A and B) were isolated from Bacillus thuringiensis var. israelensis crystals using ion‐exchange chromatography. Protein A was found to have haemolytic and neurotoxic activities. Inhibition of nerve conduction in the sixth abdominal ganglion of the American cockroach was observed following application of protein A. Protein A was found to be haemolytic to human and rabbit erythrocytes. Protein B did not exhibit any of these activities.