Open AccessInhibition of bacterial adhesion by an artificial surfactant
Author(s) -
Erne Angelika M.,
Werner Rolf G.,
Reifenrath Rainer
Publication year - 1984
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1984.tb01064.x
Subject(s) - klebsiella pneumoniae , pulmonary surfactant , adhesion , chemistry , bacteria , microbiology and biotechnology , embryonic stem cell , antimicrobial , cytotoxic t cell , cell adhesion , escherichia coli , biochemistry , biology , in vitro , genetics , organic chemistry , gene
Non‐cytotoxic and non‐antimicrobial concentrations of an artificial surfactant inhibited the adhesion of 14 C‐radiolabelled Klebsiella pneumoniae WG14 to embryonic lung epithelial cells L‐132. The minimal antiadhesive concentration was 200 ng · ml −1 . In a dynamic adhesion test model, already adhering bacteria were removed from the epithelial cell surface by the surfactant. The antiadhesive action might be based on protection of the epithelial cells.