Open AccessInteraction between human polymorphonuclear leukocytes and Chlamydia trachomatis
Author(s) -
Söderlund Gustaf,
Dahlgren Claes,
Kihlström Erik
Publication year - 1984
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1984.tb00347.x
Subject(s) - chlamydiae , chlamydia trachomatis , chlamydiaceae , chemiluminescence , microbiology and biotechnology , respiratory burst , serotype , chlamydiales , chlamydia , antiserum , biology , antibody , granulocyte , immunology , phagocytosis , virology , chemistry , organic chemistry
The association of Chlamydia trachomatis serotypes E and L1 with human polymorphonuclear leukocytes (PMNL) and the ability of these chlamydiae to induce a chemiluminescence response in PMNL were recorded. C. trachomatis unequivocally activated a respiratory burst in PMNL. Despite similar association with PMNL, serotype E activated the PMNL significantly more than serotype L1. Type‐specific, but not group‐specific antisera increased the chemiluminescence but not association of chlamydiae with PMNL. These results indicate that recording of chemiluminescence may be of value to estimate potential antichlamydial activity of PMNL and that type‐specific antibodies have opsonizing effect exerted subsequent to the attachment phase of chlamydiae to PMNL.