Open AccessEffect of mucoid growth of Staphylococcus aureus on its susceptibility to rabbit polymorph bactericidal factors
Author(s) -
Kolawole Deboye O.
Publication year - 1983
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1983.tb00253.x
Subject(s) - staphylococcus aureus , microbiology and biotechnology , rabbit (cipher) , chemistry , bacteria , biology , genetics , mathematics , statistics
Enhancements in the virulence properties of staphylococci after growth in vivo in rabbits have been reported earlier [1]. Such organisms subsequently showed increased resistance to killing by crude lysates [2] or soluble bactericidins (SB) of rabbit polymorphonuclear (PMN) leukocytes [3,4] and this was mimicked by growth of the original strain in plasma [4]. These findings suggested a correlation between increased resistance and enhanced virulence. Apart from growth in vivo, other cultural conditions such as growth in the high-salt, high-carbohydrate-modified 110 Staphylococcus medium have been shown to enhance the virulence of two strains of staphylococci in bovine skin [5]. The possibility that this medium would also enhance the resistance of staphylococci was therefore investigated. This paper reports enhancement in the resistance, to killing by SB, of a Staphylococcus aureus strain O used in previous studies [1-4] after growth in the modified 110 agar or in the corresponding broth medium.