Open AccessMannosephilic adhesins produced by some strains of motile Aeromonas reveal structural details of Salmonella lipopolysaccharide through the phenomenon of co‐agglutination
Author(s) -
Atkinson H.M.,
Adams D.,
Woods W.H.
Publication year - 1983
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1983.tb00138.x
Subject(s) - bacterial adhesin , salmonella , microbiology and biotechnology , aeromonas , agglutination (biology) , virulence , fimbria , biology , aeromonas caviae , lipopolysaccharide , bacteria , enterobacteriaceae , escherichia coli , antigen , biochemistry , immunology , gene , genetics
Some strains of motile Aeromonas produce lectin‐like adhesins, whose activity can be inhibited by d ‐mannose. Such strains can co‐agglutinate with some strains of Salmonella . Whether or not co‐agglutination occurs is dependent upon both the properties of the Aeromonas adhesin and the structure of the Salmonella lipopolysaccharide (LPS). These studies have enabled new structural information for Salmonella LPS to be deduced and have confirmed previous studies regarding the nature of the Aeromonas adhesin binding site. It is possible that the observed in vitro co‐agglutination between Aeromonas and Salmonella is a reflection of an in vivo situation which could modify the virulence of either or both bacteria.