Open AccessEnzymatic evidence for the operation of the FBP aldolase cleavage and TK/TA re‐arrangement variant of the RuMP cycle in Arothbacter P1
Author(s) -
Levering P.R.,
Dijkhuizen L.,
Harder W.
Publication year - 1982
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1982.tb00009.x
Subject(s) - aldolase a , enzyme , cleavage (geology) , fructose bisphosphate aldolase , rump , biochemistry , chemistry , biology , anatomy , paleontology , fracture (geology)
1. INTRODUCTION In the microbial assimilation of one-carbon compounds via the ribulose monophosphate (RUMP) pathway of formaldehyde fixation, clea- vage of hexose phosphates to C 3 fragments and regeneration of the acceptor molecule RuMP are essential steps for the continued operation of the cycle. Two modes of cleavage and two modes of re-arrangement are known and the permutation of these leads to four possible variants of the RuMP cycle [1] (Table 1). The limited published data, reviewed by Zatman [2], suggest that so far only methylotrophic organisms with the KDPGA/TA