Open AccessDetection of bla SHV , bla TEM and bla CTX‐M antibiotic resistance genes in randomly selected bacterial pathogens from the Steve Biko Academic Hospital
Author(s) -
Ehlers Marthie M.,
Veldsman Chrisna,
Makgotlho Eddy P.,
Dove Michael G.,
Hoosen Anwar A.,
Kock Marleen M.
Publication year - 2009
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.2009.00564.x
Subject(s) - biology , microbiology and biotechnology , gene , escherichia coli , antibiotic resistance , antibiotics , enterobacteriaceae , genetics
Extended‐spectrum β‐lactamases (ESBLs) are considered to be one of the most important antibiotic resistance mechanisms. This study reported the ESBL‐producing genes in 53 randomly selected clinical bacterial isolates from the Steve Biko Academic Hospital. The presence of the bla SHV , bla TEM and bla CTX‐M genes was determined, and the overall prevalence of these genes detected in this study was 87% (46/53) in comparison with the literature; these results were higher when compared with 33% for Escherichia coli in Europe and 0.8% in Denmark for similar pathogens. These research findings indicated that it is crucial to routinely monitor the prevalence of these resistance genes.