Open AccessInfluence of growth conditions on diverse polysaccharide production by Campylobacter jejuni
Author(s) -
Corcoran Adrian T.,
Moran Anthony P.
Publication year - 2007
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.2006.00178.x
Subject(s) - campylobacter jejuni , microbiology and biotechnology , polysaccharide , chemostat , biology , bacteria , bacterial capsule , virulence , biochemistry , gene , genetics
Abstract Campylobacter jejuni is the leading bacterial cause of gastroenteritis worldwide. The present study was undertaken to determine the forms of polysaccharide‐related compounds (PRCs) produced by C. jejuni and the culture conditions influencing their production. Expression of polysaccharides by C. jejuni was influenced by culture medium composition and growth phase. In addition to the production of lipooligosaccharide and capsular polysaccharide, a previously undescribed polysaccharide, not related to capsular polysaccharide, was shown to occur in C. jejuni in batch liquid and chemostat cultures. Thus, a variety of PRCs are produced by C. jejuni , and this should be considered when growing the bacterium in vitro for pathogenesis studies.