Open AccessBactericidal activity of normal cord serum (NCS) against Gram‐negative rods with sialic acid‐containing lipopolysaccharides (LPS)
Author(s) -
Mielnik Gabriela,
Gamian Andrzej,
Doroszkiewicz Włodzimierz
Publication year - 2001
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.2001.tb00516.x
Subject(s) - sialic acid , glycoconjugate , microbiology and biotechnology , biology , bacteria , gram negative bacteria , polysaccharide , biochemistry , escherichia coli , genetics , gene
Sialic acids, that are important constituents of animal tissue glycoconjugates, are also present in antigens of some bacterial strains. Capsular polysaccharides with sialic acid have been extensively studied whereas little is known on lipopolysaccharides which contain sialic acid. The susceptibility of Gram‐negative strains with sialic acid‐containing lipopolysaccharides to the bactericidal action of the sera of newborns was examined. The strains investigated showed variable sensitivity to the bactericidal action of normal cord serum.