Open AccessSensitivity of bacterial coaggregation to chelating agents
Author(s) -
Taweechaisupapong Suwimol,
Doyle R.J.
Publication year - 2000
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.2000.tb01496.x
Subject(s) - chelation , bacterial adhesin , escherichia coli , microbiology and biotechnology , biology , actinomyces , actinomycetaceae , actinomyces naeslundii , biochemistry , bacteria , chemistry , actinomycetales , streptomyces , genetics , organic chemistry , gene
Coaggregation between pairs of microorganisms was found to be inhibited by chelating agents, such as acetylacetone, citrate, EDTA and carboxymethylcellulose. Assays were conducted on eight pairs of periodontopathogens and one pair consisting of Escherichia coli and Saccharomyces cerevisiae . The inhibitory effects of the chelating agents were reversible except for Actinomyces naeslundii 12104, the adhesin of which was irreversibly inactivated. Even though the bacteria possessed different kinds of adhesins, their sensitivity to chelating agents appears to be a common property. Non‐toxic chelating agents, such as carboxymethylcellulose and citrate, may prove to be useful anti‐adhesins.