Open AccesspH6 antigen (PsaA protein) of Yersinia pestis , a novel bacterial Fc‐receptor
Author(s) -
Zav'yalov Vladimir P.,
Abramov Vyacheslav M.,
Cherepanov Peter G.,
Spirina Galina V.,
Chernovskaya Tatiana V.,
Vasiliev Anatolii M.,
Zav'yalova Galina A.
Publication year - 1996
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.1996.tb00267.x
Subject(s) - yersinia pestis , biology , microbiology and biotechnology , virulence , yersinia , antigen , fimbria , bacterial adhesin , recombinant dna , macrophage , enterobacteriaceae , bacteria , escherichia coli , immunology , in vitro , biochemistry , gene , genetics
It was found that recombinant pH6 antigen (rPsaA protein) forming virulence‐associated fimbriae on the surface of Yersinia pestis at pH 6.7 in host macrophage phagolysosomes or extracellularly in abscesses such as buboes, is a novel bacterial Fc‐receptor. rPsaA protein displays reactivity with human IgG1, IgG2 and IgG3 subclasses but does not react with rabbit, mouse and sheep IgG.