Open AccessAntimicrobial activities of black‐pigmented Gram‐negative anaerobes
Author(s) -
Höhne C.,
Neumann D.,
Jentzsch M.
Publication year - 1993
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1111/j.1574-695x.1993.tb00333.x
Subject(s) - prevotella intermedia , porphyromonas gingivalis , antimicrobial , biology , microbiology and biotechnology , periodontitis , gram , bacteroidaceae , gram negative bacteria , bacteria , escherichia coli , medicine , biochemistry , genetics , gene
The antimicrobial activities of Prevotella intermedia and Porphyromonas gingivalis isolates were tested against other species of Gram‐positive and Gram‐negative anaerobes as well as against each other. Generally, Pr. intermedia possessed significantly higher antimicrobial activity than P. gingivalis . The strongest activity of P. gingivalis towards Gram‐negative anaerobes was directed against Pr. intermedia . Cross‐sensitivity between both species was observed with strains from different lesions. Antimicrobial activity towards strains of the same species was detected only with Pr. intermedia . No correlations were found between plasmid content and antimicrobial activity. It was concluded that the inhibitory potency of Pr. intermedia could be one reason for the high proportion of black‐pigmented Gram‐negative anaerobes in the subgingival flora of periodontitis lesions.