Open AccessSleep Deprivation and Epilepsy
Author(s) -
Malow Beth A.
Publication year - 2004
Publication title -
epilepsy currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 22
eISSN - 1535-7511
pISSN - 1535-7597
DOI - 10.1111/j.1535-7597.2004.04509.x
Subject(s) - sleep deprivation , epilepsy , ictal , medicine , neuroscience , sleep (system call) , decipher , facilitator , psychiatry , bioinformatics , psychology , cognition , computer science , operating system , social psychology , biology
A patient with epilepsy should “spend the day awake and the night asleep. If this habit be disturbed, it is not so good … worse of all when he sleeps neither night nor day.”—Hippocrates (1) This review summarizes the data for and against sleep deprivation as a facilitator of epileptic seizures and interictal epileptiform discharges. Much of these data are derived from clinical studies; however, basic science investigations are greatly needed to determine the influence of sleep deprivation on seizure susceptibility and neuronal function. Study of the effects of sleep deprivation on epilepsy may create a window of opportunity that could help decipher how seizures are triggered and facilitated, potentially providing an avenue for future interventions.