Open AccessDo Single Seizures Cause Neuronal Death in the Human Hippocampus?
Author(s) -
Rocha Luisa L.,
LopezMeraz MariaLeonor,
Niquet Jerome,
Wasterlain Claude G.
Publication year - 2007
Publication title -
epilepsy currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 22
eISSN - 1535-7511
pISSN - 1535-7597
DOI - 10.1111/j.1535-7511.2007.00178.x
Subject(s) - status epilepticus , medicine , hippocampus , hippocampal formation , epilepsy , neuroscience , cause of death , psychiatry , disease , psychology
The question of whether repeated single seizures cause neuronal death in the adult human brain is of great clinical importance and might have broad therapeutic implications. Reviewed here are recent studies on the effects of repeated single seizures (in the absence of status epilepticus) on hippocampal volume and on neuronal death markers in blood and in surgically ablated hippocampi.