Open AccessExternal Electric Muscle Stimulation Improves Burning Sensations and Sleeping Disturbances in Patients with Type 2 Diabetes and Symptomatic Neuropathy
Author(s) -
Humpert Per M.,
Morcos Michael,
Oikonomou Dimitrios,
Schaefer Karin,
Hamann Andreas,
Bierhaus Angelika,
Schilling Tobias,
Nawroth Peter P.
Publication year - 2009
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1111/j.1526-4637.2008.00557.x
Subject(s) - medicine , type 2 diabetes , diabetes mellitus , prospective cohort study , stimulation , neuropathic pain , peripheral neuropathy , diabetic neuropathy , physical therapy , anesthesia , surgery , endocrinology
Objective. External muscle stimulation (EMS) of the thighs was previously shown to have beneficial effects in a pilot study on painful diabetic neuropathy. However, differential effects on specific symptoms of neuropathy as well as determinants of treatment response have not been described. Design. Ninety‐two type 2 diabetes patients with different neuropathic symptoms were included in a prospective uncontrolled trial. Patients were treated twice a week for 4 weeks. Symptoms were graded on numeric scales at baseline, before the second and the eighth visit. Results. Seventy‐three percent of the participants reported marked improvement of symptoms. Subjective treatment response was positively and independently associated with symptom intensity but independent of disease extent, metabolic factors, age, or gender. Total symptoms graded by patients on numerical scales decreased significantly after 4 weeks of treatment. Patients in the upper tertile of symptom intensity showed significant improvement of paresthesia, pain, numbness and most pronounced for burning sensations and sleeping disturbances. Conclusions. In an uncontrolled setting, EMS seems to be an effective treatment for symptomatic neuropathy in patients with type 2 diabetes, especially in patients with strong symptoms.