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Breast‐Specific Gamma Imaging with 99m Tc‐Sestamibi and Magnetic Resonance Imaging in the Diagnosis of Breast Cancer—A Comparative Study
Author(s) -
Brem Rachel F.,
Petrovitch Ivan,
Rapelyea Jocelyn A.,
Young Heather,
Teal Christine,
Kelly Tricia
Publication year - 2007
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/j.1524-4741.2007.00466.x
Subject(s) - medicine , magnetic resonance imaging , scintimammography , radiology , breast cancer , mammography , indeterminate , nuclear medicine , breast mri , gold standard (test) , cancer , mathematics , pure mathematics
  The purpose of this study was to compare the sensitivity and specificity of breast‐specific gamma imaging (BSGI) using a high‐resolution breast‐specific gamma camera and magnetic resonance imaging (MRI) in patients with indeterminate breast findings. Twenty‐three women with an indeterminate breast finding that required BSGI and MRI as deemed necessary by the interpreting radiologist or referring physician were included. MRI was performed on a GE 1.5T scanner and BSGI was performed on a Dilon high‐resolution breast‐specific gamma camera. All imaging findings were correlated with pathologic diagnosis. Thirty‐three indeterminate lesions were evaluated in the study. There were a total of nine pathologically confirmed cancers. There was no statistically significant difference in sensitivity of cancer detection between BSGI and MRI. BSGI demonstrated a greater specificity than MRI, 71% and 25%, respectively. BSGI has equal sensitivity and greater specificity than MRI for the detection of breast cancer.

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