Open AccessHosting the severe acute respiratory syndrome coronavirus: specific cell factors required for infection
Author(s) -
De Haan Cornelis A. M.,
Rottier Peter J. M.
Publication year - 2006
Publication title -
cellular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.542
H-Index - 138
eISSN - 1462-5822
pISSN - 1462-5814
DOI - 10.1111/j.1462-5822.2006.00744.x
Subject(s) - biology , coronavirus , covid-19 , respiratory system , viral replication , virology , immunology , betacoronavirus , middle east respiratory syndrome coronavirus , intensive care medicine , virus , medicine , disease , outbreak , anatomy , infectious disease (medical specialty)
Summary As with all viruses, the severe acute respiratory syndrome coronavirus (SARS‐CoV) utilizes specific host cell factors during its infection cycle. Some of these factors have been identified and are now increasingly scrutinized as targets to intervene with infection. In this brief review, we describe the current understanding of how the SARS‐CoV is able to use the cellular machinery for its replication.