Open AccessPhotoprotective activity of scallop shell water‐extract in keratinocyte cells
Author(s) -
TORITA Akane,
LIU Yun Chun,
HASEGAWA Yasushi
Publication year - 2004
Publication title -
fisheries science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.412
H-Index - 64
eISSN - 1444-2906
pISSN - 0919-9268
DOI - 10.1111/j.1444-2906.2004.00886.x
Subject(s) - scallop , keratinocyte , hydrogen peroxide , chemistry , antioxidant , microbiology and biotechnology , lipid peroxidation , shell (structure) , biochemistry , in vitro , biology , fishery , materials science , composite material
The photoprotective activity of the scallop shell water‐extract was investigated using cultured rat skin keratinocyte cells. It was found that the scallop shell water‐extract protected keratinocyte cells against ultraviolet (UV)‐B‐induced damage. The scallop shell water‐extract had protective effects against hydrogen peroxide (H 2 O 2 ) in skin keratinocyte cells and also showed 1,1‐diphenyl‐2‐picrylhydrazyl radical scavenging activity and lipid peroxidation inhibitory activity. In addition, the scallop shell water‐extract promoted proliferation of keratinocyte cells. The scallop shell water‐extract may protect skin keratinocyte cells against UV‐B‐induced damage through two factors; antioxidant activity and growth‐promoting activity in skin keratinocyte cells. These results suggest utilization of the scallop shell water‐extract as materials for protecting skin.