Open AccessTemporal trends and outcomes in utilisation of transcatheter and surgical aortic valve therapies in aortic valve stenosis patients with heart failure
Author(s) -
Alkhadra Yasser,
Sattar Yasar,
Ullah Waqas,
Moussa Pacha Homam,
Baibars Motaz,
Darmoch Fahed,
AbuMahfouz Mohammed,
Afonso Luis,
Devireddy Chandan,
Anwaruddin Saif,
Sorajja Paul,
Ajmal Rasikh,
Kwok Chun Shing,
Asfour Abedelrahim I.,
Zehr Kenton,
Mamas Mamas A.,
Alraies M. Chadi
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13711
Subject(s) - medicine , cardiology , heart failure , aortic valve replacement , ejection fraction , stenosis , valve replacement , aortic valve stenosis , aortic valve , odds ratio , comorbidity
s & Aims Heart failure (HF) is a common comorbidity in patients undergoing surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). We sought to access the temporal trends and outcomes of TAVR or SAVR in HF patients. Method The NIS database from 2011‐2014 was queried for patients that underwent TAVR or SAVR and were subsequently diagnosed with HF. Temporal trends in the utilisation of TAVR or SAVR in HF patients were analysed. Results Among 27 982 patients who were diagnosed with HF of whom 17 681 (63.2%) had heart failure with reduced ejection fraction (HFrEF) while 10 301 (36.8%) had heart failure with preserved ejection fraction (HFpEF), 9049 (32.3%) underwent TAVR and 16 933 (76.7%) underwent SAVR. Patients with HFrEF and HFpEF had higher utilisation of TAVR compared with SAVR over the course of the study period ( P trend < .001). TAVR was associated with lower mortality [2.8% in 2012 and 1.8% in 2014 ( P .013)] compared with SAVR. Similarly, multiple logistic regression showed a statistically significant lower in‐hospital mortality in the TAVR group compared with SAVR (aOR 0.634; CI 0.504, 0.798, P < .001). Conclusion For patients with severe aortic valve stenosis and heart failure who undergo aortic valve intervention, TAVR is associated with less odds of in‐hospital mortality compared with SAVR.