Open AccessA multinational observational investigation of illness perceptions and quality of life among patients with a Fontan circulation
Author(s) -
Holbein Christina E.,
Fogleman Nicholas D.,
Hommel Kevin,
Apers Silke,
Rassart Jessica,
Moons Philip,
Luyckx Koen,
Sluman Maayke A.,
Enomoto Junko,
Johansson Bengt,
Yang HsiaoLing,
Dellborg Mikael,
Subramanyan Raghavan,
Jackson Jamie L.,
Budts Werner,
Kovacs Adrienne H.,
Morrison Stacey,
Tomlin Martha,
Gosney Kathy,
Soufi Alexandra,
Eriksen Katrine,
Thomet Corina,
Berghammer Malin,
Alday Luis,
Callus Edward,
Fernandes Susan M,
Caruana Maryanne,
Menahem Samuel,
Cook Stephen C.,
Rempel Gwen R.,
White Kamila,
Khairy Paul,
Kutty Shelby,
Veldtman Gruschen
Publication year - 2018
Publication title -
congenital heart disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 42
eISSN - 1747-0803
pISSN - 1747-079X
DOI - 10.1111/chd.12583
Subject(s) - medicine , psychosocial , observational study , quality of life (healthcare) , anxiety , heart disease , fontan procedure , psychological intervention , physical therapy , cardiology , pediatrics , psychiatry , nursing
Objective First, to compare QOL and illness perceptions between patients with a Fontan circulation and patients with anatomically simple defects (ie, atrial septal defects [ASD] or ventricular septal defects [VSD]). Second, to explore illness perceptions as a mediator of the association between congenital heart disease (CHD) diagnosis and QOL. Design Cross‐sectional observational study. Setting Twenty‐four cardiology centers from 15 countries across five continents. Patients Four hundred thirty‐five adult patients with congenital heart disease (177 Fontan and 258 ASD/VSD) ages 18‐83 years. Outcome Measures QOL and illness perceptions were assessed by the Satisfaction With Life Scale and the Brief Illness Perceptions Questionnaire, respectively. Results Patients with a Fontan circulation reported lower QOL (Wald Z = −3.59, p = <.001) and more negative perceptions of their CHD (Wald Z = −7.66, p < .001) compared with patients with ASD/VSD. After controlling for demographics, anxiety, depressive symptoms, and New York Heart Association functional class, path analyses revealed a significant mediation model, αβ = 0.15, p = .002, 95% CI = 0.06‐0.25, such that CHD diagnosis was indirectly related to QOL through illness perceptions. Conclusions The Fontan sample's more negative perceptions of CHD were likely a reflection of life with a more complex defect. Illness perceptions appear to account for unique differences in QOL between groups of varying CHD complexity. Psychosocial screening and interventions may be important treatment components for patients with CHD, particularly those with Fontan circulations.