Open AccessResting Energy Expenditure at 3 Months of Age Following Neonatal Surgery for C ongenital H eart D isease
Author(s) -
Irving Sharon Y.,
MedoffCooper Barbara,
Stouffer Nicole O.,
Schall Joan I.,
Ravishankar Chitra,
Compher Charlene W.,
Marino Bradley S.,
Stallings Virginia A.
Publication year - 2013
Publication title -
congenital heart disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.828
H-Index - 42
eISSN - 1747-0803
pISSN - 1747-079X
DOI - 10.1111/chd.12035
Subject(s) - medicine , anthropometry , resting energy expenditure , pediatrics , heart disease , prospective cohort study , neonatal intensive care unit , head circumference , energy expenditure , birth weight , pregnancy , biology , genetics
Objective Infants with C ongenital H eart D isease ( CHD ) often exhibit growth failure. This can affect anthropometric and neurodevelopmental outcomes well into childhood. To determine the resting energy expenditure ( REE ), body composition, and growth in infants with CHD at 3 months of age, with the secondary aim to identify predictors of REE as compared with healthy infants. Design and Methods. This descriptive study is a subanalysis of a prospective study investigating predictors of growth in postoperative infants with CHD compared with healthy infants. Growth measurements, REE , and body composition were obtained in all infants. Analysis included chi‐square for association between categorical variables, t ‐tests, ANOVA and ANCOVA. Outcome measures included the REE as determined by indirect calorimetry, anthropometric z‐scores and body composition at 3 months of age. Setting. Participants were recruited from the Cardiac Intensive Care Unit of a large, urban, pediatric cardiac center and pediatric primary care practices. Results. The analysis included 93 infants, 44 (47%) with CHD . Of the infants with CHD , 39% had single ventricle ( SV ) physiology. There was no difference in REE related to cardiac physiology between infants with CHD and healthy infants or between infants with SV and biventricular ( BV ) physiology. Anthropometric z‐scores for weight (−1.1 ± 1.1, P < 0.001), length (−0.7 ± 1.1, P < 0.05), and head circumference (−0.6 ± 1.2, P < 0.001) were lower in infants with CHD at 3 months of age. The percentage of body fat (% FAT ) in postoperative infants with SV (24% ± 6, P = 0.02) and BV (23% ± 5, P < 0.001) physiology were lower than in healthy infants (27% ± 5), with no difference in REE . Conclusion. A t 3 months of age, there was no difference in REE between postsurgical infants with CHD and healthy infants. Infants with CHD had lower growth z‐scores and % FAT . These data demonstrate decreased % FAT contributed to growth failure in the infants with CHD .