Associations between clinical features and therapy with macrophage subpopulations and T cells in inflammatory lesions in the aorta from patients with Takayasu arteritis | Zendy

Santos J. P. | Zendy; Artigiani Neto R. | Zendy; Mangueira C. L. P. | Zendy; Filippi R. Z. | Zendy; Gutierrez P. S. | Zendy; Westra J. | Zendy; Brouwer E. | Zendy; Souza A. W. S. | Zendy

Open Access

Associations between clinical features and therapy with macrophage subpopulations and T cells in inflammatory lesions in the aorta from patients with Takayasu arteritis

Author(s) -

Santos J. P.,

Artigiani Neto R.,

Mangueira C. L. P.,

Filippi R. Z.,

Gutierrez P. S.,

Westra J.,

Brouwer E.,

Souza A. W. S.

Publication year - 2020

Publication title -

clinical & experimental immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.329

H-Index - 135

eISSN - 1365-2249

pISSN - 0009-9104

DOI - 10.1111/cei.13489

Subject(s) - cd68 , medicine , macrophage , giant cell arteritis , cd8 , pathology , vasculitis , immunology , cd86 , cd20 , prednisone , t cell , immune system , immunohistochemistry , biology , disease , biochemistry , in vitro

M1 macrophages were more frequent in TAK and atherosclerotic patients compared to heart transplant donors. The expression of CD206 is higher than the expression of CD86 in the aorta from TAK patients. T cells were associated with histological disease activity and with prednisone use in TAK.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research