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European research networks to facilitate drug research in children
Author(s) -
Turner Mark A.,
Cheng Katharine,
Wildt Saskia,
Hildebrand Heidrun,
Attar Sabah,
Rossi Paolo,
Bonifazi Donato,
Ceci Adriana,
Claverol Joana,
Nafria Begonya,
Giaquinto Carlo
Publication year - 2022
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/bcp.14545
Subject(s) - translational research , clinical trial , context (archaeology) , medicine , translational science , work (physics) , drug development , public relations , engineering ethics , political science , drug , pharmacology , engineering , pathology , mechanical engineering , paleontology , biology
Paediatric drug development faces several barriers. These include fragmentation of stakeholders and inconsistent processes during the conduct of research. This review summarises recent efforts to overcome these barriers in Europe. Two exemplar initiatives are described. The European Paediatric Translational Research Infrastructure facilitates preclinical research and other work that underpins clinical trials. conect4children facilitates the design and implementation of clinical trials. Both these initiatives listen to the voices of children and their advocates. Coordination of research needs specific effort that supplements work on science, resources and the policy context.