Open AccessBifidobacterium animalis ssp. lactis BI 07 modulates the tumor necrosis factor alpha‐dependent imbalances of the enterocyte‐associated intestinal microbiota fraction
Author(s) -
Centanni Manuela,
Turroni Silvia,
Rampelli Simone,
Biagi Elena,
Quercia Sara,
Consolandi Clarissa,
Severgnini Marco,
Brigidi Patrizia,
Candela Marco
Publication year - 2014
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/1574-6968.12515
Subject(s) - bifidobacterium animalis , enterocyte , probiotic , microbiology and biotechnology , biology , bifidobacterium , tumor necrosis factor alpha , immunology , bacteria , lactobacillus , biochemistry , small intestine , genetics
Using a previously developed in vitro model to characterize the enterocyte‐adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI 07 to modulate the inflammation‐dependent dysbioses of the enterocyte‐adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI 07 is effective in limiting the increase of pro‐inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.