Open AccessS chizosaccharomyces pombe grows exponentially during the division cycle with no rate change points
Author(s) -
Cooper Stephen
Publication year - 2013
Publication title -
fems yeast research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.991
H-Index - 92
eISSN - 1567-1364
pISSN - 1567-1356
DOI - 10.1111/1567-1364.12072
Subject(s) - exponential growth , schizosaccharomyces pombe , biology , cell division , cell cycle , division (mathematics) , linear growth , growth rate , exponential function , microbiology and biotechnology , cell , genetics , yeast , mathematics , mathematical analysis , arithmetic , saccharomyces cerevisiae , geometry
Length measurements during the division cycle of 86 individual S chizosaccharomyces pombe cells demonstrate that length grows exponentially with no change in the growth rate and no rate change point ( RCP ) observed for any cell. These results support the proposal that length extension, or cell growth, is exponential during the division cycle. The finding of exponential growth during the cell cycle is significant because these results challenge and contradict the current, consensus, widely believed, and widely accepted view that growth of S . pombe during the division cycle is complex with ranges of linear growth changing at proposed RCP s. Biochemical synthetic patterns support and explain the observed exponential cell growth. Exponential growth of S . pombe is consistent with, and supports, the central tenets of the continuum model.