Open AccessYeast response to LA virus indicates coadapted global gene expression during mycoviral infection
Author(s) -
McBride Robert C.,
Boucher Nathalie,
Park Derek S.,
Turner Paul E.,
Townsend Jeffrey P.
Publication year - 2013
Publication title -
fems yeast research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.991
H-Index - 92
eISSN - 1567-1364
pISSN - 1567-1356
DOI - 10.1111/1567-1364.12019
Subject(s) - biology , host (biology) , asexual reproduction , gene , virus , yeast , genetic fitness , coinfection , giant virus , virology , genetics , genome
Abstract Viruses that infect fungi have a ubiquitous distribution and play an important role in structuring fungal communities. Most of these viruses have an unusual life history in that they are propagated exclusively via asexual reproduction or fission of fungal cells. This asexual mode of transmission intimately ties viral reproductive success to that of its fungal host and should select for viruses that have minimal deleterious impact on the fitness of their hosts. Accordingly, viral infections of fungi frequently do not measurably impact fungal growth, and in some instances, increase the fitness of the fungal host. Here we determine the impact of the loss of coinfection by LA virus and the virus‐like particle M 1 upon global gene expression of the fungal host S accharomyces cerevisiae and provide evidence supporting the idea that coevolution has selected for viral infection minimally impacting host gene expression.