Open AccessDigital Therapeutic Platform for Management of Systemic Lupus Erythematosus
Author(s) -
Vanessa Rudin,
Eric Lubow,
Nicole Bundy,
Millennia Lytle,
Martin Culjat,
Mette Dyhrberg
Publication year - 2020
Publication title -
2020 42nd annual international conference of the ieee engineering in medicine and biology society (embc)
Language(s) - English
Resource type - Conference proceedings
ISSN - 2694-0604
DOI - 10.1109/embc44109.2020.9175209
Subject(s) - bioengineering
Systemic lupus erythematosus (SLE) is a complex, multi-system autoimmune disease of unclear etiology that causes significant morbidity and, in severely affected patients, early mortality. Despite efforts from academic and private research entities, pharmaceutical companies, and patient advocacy groups, and hundreds of millions of dollars in spending, numerous gaps in care still exist. A digital therapeutic platform is described that uses self-tracking technology, analytics, and telehealth coaching to identify and remove possible dietary and/or other lifestyle triggers of SLE. A clinical proof of concept study was performed with 18 SLE patients over a 12 week program. All participants reported improvements in their symptoms, including pain, fatigue, digestive, and other physical symptoms.Clinical Relevance— This study demonstrates the technical and clinical feasibility of a digital therapeutic platform to improve the health-related quality of life in patients with systemic lupus erythematosus.