Multiple Sclerosis Detection Based on Biorthogonal Wavelet Transform, RBF Kernel Principal Component Analysis, and Logistic Regression
Author(s) -
Shuihua Wang,
Tianming Zhan,
Yi Chen,
Yin Zhang⋆,
Ming Yang,
Huimin Lu,
Hainan Wang,
Bin Liu,
Preetha Phillips
Publication year - 2016
Publication title -
ieee access
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 127
ISSN - 2169-3536
DOI - 10.1109/access.2016.2620996
Subject(s) - principal component analysis , kernel principal component analysis , biorthogonal system , pattern recognition (psychology) , logistic regression , biorthogonal wavelet , kernel (algebra) , artificial intelligence , wavelet transform , principal component regression , wavelet , computer science , mathematics , kernel method , statistics , support vector machine , combinatorics
To detect multiple sclerosis (MS) diseases early, we proposed a novel method on the hardware of magnetic resonance imaging, and on the software of three successful methods: biorthogonal wavelet transform, kernel principal component analysis, and logistic regression. The materials were 676 MR slices containing plaques from 38 MS patients, and 880 MR slices from 34 healthy controls. The statistical analysis showed our method achieved a sensitivity of 97.12±.14%, a specificity of 98.25±0.16%, and an accuracy of 97.76±0.10%. Our method is superior to five state-of-the-art approaches in MS detection.
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