Open AccessThe structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification
Author(s) -
Fu TianMin,
Liu Xiang,
Li Lanfen,
Su XiaoDong
Publication year - 2010
Publication title -
acta crystallographica section f
Language(s) - English
Resource type - Journals
ISSN - 1744-3091
DOI - 10.1107/s1744309110018944
Subject(s) - streptococcus mutans , transfer rna , microbiology and biotechnology , chemistry , biology , biochemistry , genetics , bacteria , rna , gene
Members of the Sua5_YciO_YrdC protein family are found in both eukaryotes and prokaryotes and possess a conserved α/β twisted open‐sheet fold. The Escherichia coli protein YrdC has been shown to be involved in modification of tRNA. The crystal structure of smu.1377c, a hypothetical protein from Streptococcus mutans , has been determined to 2.25 Å resolution. From structure analysis and comparison, it is shown that smu.1377c is a member of the Sua5_YciO_YrdC family and that it may play the same role as E. coli YrdC.