Open AccessThe high‐resolution structure of the extracellular domain of human CD69 using a novel polymer
Author(s) -
Kolenko Petr,
Skálová Tereza,
Vaněk Ondřej,
Štěpánková Andrea,
Dušková Jarmila,
Hašek Jindřich,
Bezouška Karel,
Dohnálek Jan
Publication year - 2009
Publication title -
acta crystallographica section f
Language(s) - English
Resource type - Journals
ISSN - 1744-3091
DOI - 10.1107/s1744309109043152
Subject(s) - dimer , ethylene glycol , resolution (logic) , polymer , crystallography , materials science , extracellular , crystal structure , adipate , monomer , chemistry , polymer chemistry , biochemistry , organic chemistry , artificial intelligence , computer science , composite material
The structure of the extracellular domain of human CD69 has been determined by single‐crystal X‐ray diffraction. The structure refined to 1.37 Å resolution provides further details of the overall structure and the asymmetric interface between the monomers in the native dimer. The protein was crystallized using di[poly(ethylene glycol)] adipate, which also served as a cryoprotectant. This is the first report of a crystal structure determined using crystals grown with this polymer.