α‐Artemether
Author(s) -
Butcher Ray J.,
Jasinski Jerry P.,
Yathirajan H. S.,
Bindya S.,
Narayana B.
Publication year - 2007
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536807029108
Subject(s) - artesunate , artemether , ring (chemistry) , derivative (finance) , heptane , chemistry , pyran , stereochemistry , hexane , artemisinin , malaria , organic chemistry , plasmodium falciparum , biology , economics , financial economics , immunology
The title compound, C 16 H 26 O 5 , a derivative of the antimalaria compound artesunate, consists primarily of three substituted ring systems fused together. A cyclohexane ring (distorted chair configuration) fused to a tetrahydropyran group (normal chair) is adjacent to an oxacycloheptane unit containing an endoperoxide bridge, giving the molecule a unique three‐dimensional arrangement.
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