Open Access(–)‐(4 R ,5 S )‐3‐[2( R )‐(4‐Chlorophenyl)propionyl]‐4‐methyl‐5‐phenyloxazolidin‐2‐one
Author(s) -
Chavda Sameer,
Eames Jason,
Flinn Anthony,
Motevalli Majid,
Malatesti Nela
Publication year - 2006
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536806031837
Subject(s) - derivative (finance) , medicinal chemistry , chemistry , chloride , crystal structure , atom (system on chip) , stereochemistry , crystallography , organic chemistry , computer science , parallel computing , financial economics , economics
The title compound, C 19 H 18 ClNO 3 , is formed from enantiomerically pure (+)‐(4 R ,5S)‐4‐methyl‐5‐phenyl‐2‐oxazolidinone and racemic 2‐(4‐chlorophenyl)propanoyl chloride. The crystal structure resembles closely that of the comparable (4‐methylphenyl)propionyl derivative, although the two structures differ in the nature of the intermolecular contacts to the Cl atom and methyl group.