Open Access(–)‐(4 R ,5 S )‐4‐Methyl‐3‐[2( R )‐(4‐methylphenyl)propionyl]‐5‐phenyloxazolidin‐2‐one
Author(s) -
Chavda Sameer,
Eames Jason,
Flinn Anthony,
Motevalli Majid,
Malatesti Nela
Publication year - 2006
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536806031825
Subject(s) - substituent , ring (chemistry) , chemistry , medicinal chemistry , chloride , methyl group , stereochemistry , group (periodic table) , organic chemistry
In the title compound, C 20 H 21 NO 3 , formed from enantiomerically pure (+)‐(4 R ,5S)‐4‐methyl‐5‐phenyl‐2‐oxazolidinone and racemic 2‐(4‐methylphenyl)propanoyl chloride, the two carbonyl groups are oriented anti to each other, and the methyl group of the (4‐methylphenyl)propionyl substituent lies close to the mean plane of the five‐membered ring.