A thio­phene‐based aza­cryptand Mannich base: 15,35‐dipropyl‐2,5,8,22,25,28‐hexa­oxa‐12,18,32,38‐tetra­thia‐15,35‐diaza­penta­cyclo­[29.5.5.5.0.0]tetra­conta‐1(37),9(13),10,17(21),19,29(33),30,39‐octa­ene

The mol­ecule of the title compound, C 34 H 46 N 2 O 6 S 4 is composed of four thio­phene rings bridged by two –O(CH 2 ) 2 O– and two –CH 2 (NC 2 H 5 )CH 2 – chains. The macrocyclic mol­ecule possesses a center of symmetry. In the crystal structure, the mol­ecules are bridged by C—H⋯O inter­actions, forming chains along the a axis.