Powder study of chlorothiazide N , N ‐dimethylformamide solvate

The crystal structure of the title compound [systematic name: 6‐chloro‐4 H ‐1,2,4‐benzothiadiazine‐7‐sulfonamide 1,1‐dioxide– N , N ‐dimethylformamide (1/1)], C 7 H 6 ClN 3 O 4 S 2 ·C 3 H 7 NO, was solved by simulated annealing from laboratory X‐ray powder diffraction data collected at 100 K. Subsequent Rietveld refinement, using data collected to 1.5 Å resolution, yielded an R wp of 0.050. Hydrogen bonds to N , N ‐dimethylformamide form the rungs of a ladder motif, which is further stabilized by a π⋯halogen dimer interaction. The benzene rings in adjacent ladders engage with each other in an offset face‐to‐face π–π interaction.