Hydrochlorothiazide  N , N ‐dimethylformamide solvate | Zendy

Johnston Andrea | Zendy; Kennedy Alan R. | Zendy; Florence Alastair J. | Zendy

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Hydrochlorothiazide N , N ‐dimethylformamide solvate

Author(s) -

Johnston Andrea,

Kennedy Alan R.,

Florence Alastair J.

Publication year - 2006

Publication title -

acta crystallographica section e

Language(s) - English

Resource type - Journals

ISSN - 1600-5368

DOI - 10.1107/s1600536806011391

Subject(s) - hydrochlorothiazide , dimethylformamide , benzothiadiazine , chemistry , solvent , molecule , sulfonamide , hydrogen bond , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry , endocrinology , medicine , blood pressure

Hydrochlorothiazide forms a 1:1 solvate with N , N ‐dimethylformamide (systematic name: 6‐chloro‐3,4‐dihydro‐2 H ‐1,2,4‐benzothiadiazine‐7‐sulfonamide‐1,1‐dioxide dimethylformamide solvate), C 7 H 8 ClN 3 O 4 S 2 ·C 3 H 7 NO. The compound crystallizes with two molecules of hydrochlorothiazide and two solvent molecules in the asymmetric unit and displays an extensive hydrogen‐bonding network.

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