Open Access5‐Fluorouracil–2,2,2‐trifluoroethanol (1/1)
Author(s) -
Hulme Ashley T.,
Tocher Derek A.
Publication year - 2005
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536805032198
Subject(s) - uracil , hydrogen bond , chemistry , ethanol , fluorouracil , stereochemistry , combinatorial chemistry , medicinal chemistry , biochemistry , organic chemistry , dna , molecule , chemotherapy , genetics , biology
The title compound, C 4 H 3 FN 2 O 2 ·C 2 H 3 F 3 O, crystallizes with one 5‐fluorouracil and one 2,2,2‐trifluoroethanol molecule in the asymmetric unit. The 5‐fluorouracil molecules are linked into a chain primarily via N—H⋯O hydrogen bonds, with the 2,2,2‐trifluoroethanol molecules attached to this via O—H⋯O hydrogen bonds.