Open AccessCarbamazepine N,N ‐dimethylformamide solvate
Author(s) -
Johnston Andrea,
Florence Alastair J.,
Kennedy Alan R.
Publication year - 2005
Publication title -
acta crystallographica section e
Language(s) - English
Resource type - Journals
ISSN - 1600-5368
DOI - 10.1107/s1600536805012535
Subject(s) - moiety , carbamazepine , dimer , amide , hydrogen bond , chemistry , crystal structure , medicinal chemistry , stereochemistry , crystallography , molecule , organic chemistry , medicine , psychiatry , epilepsy
In the title compound, C 15 H 12 N 2 O·C 3 H 7 NO, carbamazepine molecules form the R 2 2 (8) N—H⋯O hydrogen‐bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The molecules of N , N ‐dimethylformamide are located between adjacent carbamazepine dimers and form an N—H⋯O hydrogen bond to the anti ‐oriented NH group of the carboxamide moiety of carbamazepine.